Cell Lysis Homogenizers
Our unique HPH systems offer advantages over the following cell lysis methods - sonication, enzymatic / chemical lysis / freeze thaw ... and other methods also.
Cell Lysis - our advantages
Our versatile systems are easier to scale-up to production volumes and offer less time-consuming processing.
Increased cell disruption efficiency which may result in higher output and better yields of cell contents.
Our higher pressure capability is more effective at breaking open cells with tough walls - for example some Yeast cells (Pichia), Bacteria (Staphylococcus) and plant cells - e.g creation of nanocellulose.
Sophisticated temperature control options - pre-process or at the point of lysis or for rapid post processing cooling.
Maintaining cell contents quality and purity (change).
When compared to sonication less heat is generated, less noise and less aerosols.
Process volumes from 275ml per minute / 16 l/h in the Lab to in excess of 1000 l/h for production systems.
Easy to use and clean. CIP and SIP capacity. Provision of DQ /IQ /OQ documentation.
Adjustable pressure from 1500 psi up to ultra high - 60,000 psi / 4100 bar / 410 Mpa
Lab Cell Homogenizer
Production scale system
Fig A, B - Unprocessed Yeast suspension.
Fig C, D, E - Processed Yeast suspension after Cell Lysis under different pressure settings using our 'STANSTED Pressure Cell Homgeniser' above
Fig A
Fig B