Our Ultra High Pressure Homogenizing systems offer unrivalled performance, with repeatable results, for continuous high shear fluid processing in excess of 2000 l/h for production applications including particle size reduction, nanoemulsions, cell lysis and liposome preparation.


Our 085 and 1000 series "Hy-Drive" systems have been developed to meet the special requirements associated with Pharmaceutical, Biotechnology, Nutraceuticals and Chemical processing sectors.

Our systems are designed to provide compliance with cGMP and FDA-GMP and can be offered with IQ / OQ documentation, full materials certification. 21 CFR part 11 compliance can be provided, and PLC with HMI and touch screen interface with integral data logging of primary process parameters.

For production pharmaceutical applications, our systems are designed with excellent 'Clean in Place' (CIP) and 'Steam in Place' (SIP) capability.

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UHPH - Production Homogenizers - features and benefits

  Multiple synchronised intensifiers for continuous high shear fluid processing with adjustable working pressures up to 60,000 psi (4200 bar).

  Processing volumes in excess of 2000 l/h with repeatable processing results.

  Multiple options for temperature control, including pre-heating and rapid post process cooling.

  Full documentation packs, provision of DQ/IQ/OQ.

  'Clean in Place' (CIP) and 'Steam in Place' (SIP) capability.

  Processing options of piston gap valves and micro channels (interaction chambers) to ensure optimised and customised processing to match the application.

  Wetted surfaces are polished to meet typical industrial pharmaceutical and biotech requirements.

  Easy to use, easy to maintain and high operating reliability ensures lower ongoing operating costs than other systems.

  System control is provided through a dedicated PLC with HMI and touch screen interface with integral data logging of primary process parameters.

Production Homogenizer in pharmaceutical clean room.

Production Homogenizer - 7575 model

Production scale Pharmaceutical application with feed and discharge reservoirs.

Stansted Production Homogenizer - Biotech Research

Stansted 1000 series Production Homogenizer

Stansted Production Homogenizer

Homogenizing valves - Piston Gap and Micro-Channel Device (interaction chamber)

Homogenizing valve - spindle seat arrangement

Homogenizer valve - both Piston Gap and Micro Channel

Contact Us to discuss which Production models best meet your requirements.

Patented Construction.

A unique intensifier design, referred to as Hyd-Lok, uses a hydraulic clamping mechanism, rather than bolts, to lock the intensifier assemblies together during operation. The ability to open the intensifier assembly at the push of a button (without tools) offers huge benefits for routine cleaning, inspection and maintenance, which can all be handled easily by the operator.

Reliability and durability.

Robust electro-hydraulic drive system driving one or two (electronically synchronized) intensifiers. Each intensifier makes 2 to 12 strokes per minute, keeping seal and other component fatigue to a minimum, resulting in reliable operation and lower cost of ownership.

Simple operation.

Sophisticated PLC-based control and monitoring system provides the operator with menu driven operation and fault diagnosis. The PLC digitally displays the system’s temperature and pressure and has a communications port to allow connection to PCs or suitably interfaced data loggers.

Temperature Control.

Sophisticated temperature control systems, enabling pre-cooling or pre-heating (as needed for processing liposomes), post-cooling, and maintaining the process section at a constant temperature.

Easy to Service.

The wetted assemblies are extremely easy to disassemble, clean, inspect and reassemble.

Reliability and durability.

Robust electro-hydraulic drive system driving one or two (electronically synchronized) intensifiers. Each intensifier makes 2 to 12 strokes per minute, keeping seal and other component fatigue to a minimum, resulting in reliable operation and lower cost of ownership.

085 production homogenizer internal.jpeg

Production Homogenizer - 085 model

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