In addition to the features above our scalable technology can also offer the following benefits listed below over other protein extraction techniques such as Chromatography and Sonication.
Benefits for Protein Purification
Extracted proteins are more likely to be in their natural form as less (or no) solvents and enzymes may be used.
High shear speed and cooling can minimise the effects of proteases which may digest some types of intracellular proteins.
Adjustable process parameters can provide more controllable cell lysis for intact protein recovery.
Multiple options for temperature control including pre-heating and rapid post process cooling.
Features and Advantages of our Technology
Variable flow rates from 1m to 275ml per minute - 16 L/h for Lab and in excess of 2000 l/h for production.
Adjustable pressure from 1,500 psi to 60,000 psi (4100 bar).
Easy to clean and sterilize. CIP and SIP. Provision of DQ /IQ /OQ documentation.
Interchangeable processing cells from - 1 ml up to 32 ml sample size.
The Lab apparatus used for cell lysis / disruption is often referred to as 'French Press' ®.
Our 'Stansted' range of Cell Disruptors provide an improved modern version of the traditional 'French Press' ®. - learn more here
Lab Homogenizer - Cell Lysis - Protein Purification
Production volume Protein Purification
Industry-leading, fully featured systems from 20 L/h to 2000 L/h.
Disrupting / Homogenising Valve Options.
Type 1 - High Shear Piston Gap.
Type 2 - Micro Channel Device.